A patient-driven movement to accelerate Long Covid Research
Million people with Long Covid1
$386B
Economic cost of Long Covid to the USA to date2
We believe that Long Covid may be a persistent SARS-CoV-2 infection. Whilst there are many theories regarding the pathophysiology – including microclotting, reactivated pathogens, and autoimmunity – persistent infection ties all these theories together. SARS-CoV-2 is one of many viruses which can chronically persist.
We have two focus areas as we investigate the role of persistent infection as a cause of Long Covid:
RNA for SARS-CoV-2 (pink) and the ACE2 receptor (white), found in salivary gland cells, outlined in green. Credit: NIH.
1 Symptoms lasting longer than 12 weeks. Extrapolated from UK’s ONS data, up to May 6th, 2022. Extrapolated to world population excluding China, adjusted for demographics.
2 Estimate from SolveME whitepaper Long Covid Impact on Adult Americans: Early Indicators Estimating Prevalence and Cost
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